个人介绍

教学工作

Modern Biotechnology and Bioengineering (Graduate course, by Prof. Zhong et al.)

Molecular Biochemical Engineering (Undergraduate course, by Profs. Zhong & Xia)

Metabolic Engineering (Undergraduate course, by Prof. Xia)

Metabolic Engineering and Synthetic Biology (Undergraduate course, by Prof. Xia)

Cell Culture Engineering (Undergraduate course, by Prof. Zhi-yong Li, Prof. Zhong, et al.)


研究领域

Molecular biochemical engineering, and bioreactor engineering
We have been working for platform building for efficient bioactive metabolites production by microbial systems. Our study has focused on validamycin A and ansamitocin fermentation: effects of environmental factors on antibiotics fermentation process at molecular levels of genes and enzymes; improvement of the biosynthetic pathway. By integration of engineering and molecular approach, we aim to improve antibiotics fermentation and contribute to industry.


Applied microbiology, advanced fermentation technology & systems biology
We have been studying medicinal mushroom fermentation and plant cell cultures for production of useful secondary metabolites for over 10 and 20 years, respectively. In recent years, we have done the regulation of biosynthetic processes of antitumor ganoderic acids and ginsenosides. Our research covers signal transduction engineering, bioactive metabolite production, and antitumor mechanism study.


Bioenergy and synthetic biology
Low-cost efficient production of ethanol and other chemicals using lignocellulosic hydrolysates; cooperation with Prof. YHP Zhang on production of biohydrogen by synthetic biology; role of quorum sensor in biodegradation of toxic aromatics.


Synthetic biology & systems metabolic engineering for smart biomaterials



大事记

重要事件

项目

  1. Regulation of biodegradation processes by quorum sensor and its mechanism study.

  2. 2009-01-01~2013-12-01;Biosynthesis and improvement of Pseudomonas pesticides.

  3. 2009-08-01~2012-07-01;Isolation, purification and acting mechanism study on antitumor metabolites of Cordyceps.

  4. 2012-01-01~2015-12-01;Combination of synthetic biology and reactor technology for biological hydrogen production.

  5. 2012-01-01~2016-12-01;Efficient manufacturing of new-structure metabolites.


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