研究领域

纳米给药系统、口服与透皮给药系统及吸收机理。在抗肿瘤药物纳米靶向制剂、提高难溶性或难吸收药物生物利用度及中药新剂型研究方面开展了许多工作。

论文

1. Multifunctional Nanoparticles as Nanocarrier for Vincristine Sulfate Delivery to Overcome Tumor Multidrug Resistance.Yuan Wang, Limei Dou, Huijuan He, Yi Zhang, Qi Shen.Mol Pharm.

2. Docetaxel-nicotinamide complex-loaded nanostructured lipid carriers for transdermal delivery.Xiucong Fan, Jinjin Chen, Qi Shen.Int J Pharm.

3. Folic acid and cell-penetrating peptide conjugated bifunctional nanoparticles for vincristine sulfate delivery.Jianian Chen,Shaosun Li,Qi Shen.Eur J Pharm Sci.

4. Characterization and evaluation of self-microemulsifying sustained-release pellet formulation of puerarin for oral delivery.Yi Zhang, Rui Wang, Jian Wu , Qi Shen.Int J Pharm.

5. Enhanced intestinal absorption of daidzein by borneol/menthol eutectic mixture and microemulsion.Qi Shen *, Xi Li, Xinyi Zhao.AAPS PharmSciTech.

6. Characterization and evaluation of nanostructured lipid carrier as a vehicle for oral delivery of etoposide.Tiecheng Zhang, Jianian Cheng, Yi Zhang, Qi Shen*, Weishan Pan.Eur J Pharm Sci.

7. Enhanced oral bioavailability of daidzein by self-microemulsifying drug delivery system.Qi Shen*, Xi Li, Dan Yuan, Wei Jia.Chem Pharm Bull.

8. Modulating Effect of Polyethylene glycol on the Intestinal Transport and Absorption of Prednisolone, Methylprednisolone and Quinidine in Rats by in vitro and in situ Absorption Studies.Qi Shen, Wenji Li, Yulian Lin, Naoki Okada, Takuya Fujita, Akira Yamamoto.J Pharm Pharmacol.

9. Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies.Qi Shen, Yulian Lin, Kana Wakayama, Naoki Okada, Takuya Fujita, AkiraYamamoto.Int J Pharm.